Osteopoikilosis (Spotted Bone Disease)

A 23 year old male presented with swelling of both knees. He had history of similar problem 18 months ago treated with joint aspiration and non-steroidal anti-inflammatory drugs. There was no other significant history. Clinical examination revealed another swelling of enthesitis near left ankle. His X-ray revealed osteopoikilosis. Arthritis was treated with non-steroidal anti-inflammatory drugs and settled over a period of 6-8 weeks. Osteopoikilosis is an inherited condition of small, rounded or oval, multiple, symmetric areas of bone sclerosis (increased density) occurring near growing ends and adjacent areas of bones. These densities appear in childhood and persist throughout life. They do not cause any symptoms nor require any treatment.

Osteopoikilosis 3     Osteopoikilosis 4      Osteopoikilosis Knee Effusion
       Osteopoikilosis 3                                       Osteopoikilosis 4                               Osteopoikilosis Knee Effusion


Osteopoikilosis 1Osteopoikilosis 1

Osteopoikilosis 2Osteopoikilosis 2